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To determine if a history of snoring is a risk factor for brain infarction,I conducted a case-control study of risk factors for ischemic stroke using 177 consecutive male patients aged 16-60(mean 49 years with acute brain infarction.For each patient I chose an age-matched(+/-6 years) male control.Arterial hypertension,coronary heart disease,snoring (habitually or often),and heavy drinking(>300 g/wk)were risk factors in the stepwise multiple logistic regression analysis.The odds ratio of snoring for brain infarction was 2.13.By McNemar's test this association increased strongly if a history of sleep apnea,excessive daytime sleepiness,and obesity were all present with snoring(odds ratio 8.00).My study indicates that snoring may be a risk factor for ischemic stroke, possibly because of the higher prevalence of an obstructive sleep apnea syndrome among snorers than nonsnorers. |
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